The vehicle is reported to have mounted the pavement at the scene, Mirror reported on its website.
"We are dealing with an incident on London Bridge, when we have more information we will update this twitter feed," the Metropolitan police said on its Twitter handle.
Press Trust of India reported that Scotland Yard armed officers had moved into London Bridge area after reports of the incident.
Several people are believed to be injured in what is feared to be a terror attack that took place last evening.
"We are dealing with an incident on #LondonBridge, when we have more information we will update," Metropolitan Police said on Twitter.
Hackney Police said on its Twitter handle: "If you have any footage from tonight, please DON'T share on social media. Upload to us."
Transport for London said the police had closed London Bridge and the area around it due to a major police incident, Xinhua reported.
"London Bridge: The station is closed and trains are non stopping at the request of the police," it said.
According to an eyewitness: "There was a white van driver speeding into several people. It carried on across the pavement around the traffic and towards the Shard area."
Some netizens who had witnessed the incident tweeted that they saw people got injured and the police came to deal with it.
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